Articles with "arc101" as a keyword



Abstract 7325: Pharmacologic characterization of a highly specific and potent CLDN6xCD3 T cell engager (TCE), ARC101, for the treatment of CLDN6+ cancers

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Published in 2025 at "Cancer Research"

DOI: 10.1158/1538-7445.am2025-7325

Abstract: Claudin 6 (CLDN6) is an oncofetal protein involved in tight junction formation and is responsible for regulating cell polarity, adhesion and permeability. CLDN6 has recently emerged as an ideal target for novel oncology therapeutics, given… read more here.

Keywords: cancer; arc101; cell; expression ... See more keywords