Articles with "architectural stripe" as a keyword



Interplay between CTCF-binding and CTCF-lacking regulatory elements in generating an architectural stripe at the Igh locus

Sign Up to like & get
recommendations!
Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-57373-w

Abstract: Three-dimensional genome organization orchestrates recombination and transcription of immunoglobulin heavy chain (Igh) genes. The structure of wild-type (WT) alleles includes a prominent architectural stripe that extends from a cluster of CTCF binding elements at the… read more here.

Keywords: regulatory elements; ctcf binding; architectural stripe; ctcf ... See more keywords