Genomic architecture and functional effects of potential human inversion supergenes
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DOI: 10.1098/rstb.2021.0209
Abstract: Supergenes are involved in adaptation in multiple organisms, but they are little known in humans. Genomic inversions are the most common mechanism of supergene generation and maintenance. Here, we review the information about two large… read more here.
Keywords: potential human; functional effects; effects potential; inversion ... See more keywords
Landscape of MicroRNA Regulatory Network Architecture and Functional Rerouting in Cancer
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DOI: 10.1158/0008-5472.can-20-0371
Abstract: A detailed miRNA–gene interaction map reveals extensive miRNA-mediated gene regulatory networks with mutation-induced perturbations across multiple cancers, serving as a resource for noncoding biomarker discovery and drug development. read more here.
Keywords: microrna regulatory; landscape microrna; regulatory network; architecture functional ... See more keywords