Targeting 3D chromosomal architecture at the RANK loci to suppress myeloma-driven osteoclastogenesis
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DOI: 10.1080/2162402x.2022.2104070
Abstract: ABSTRACT Bone disease represents a major cause of morbidity and mortality in Multiple Myeloma (MM); primarily driven by osteoclasts whose differentiation is dependent on expression of RANKL by MM cells. Notably, costimulation by ITAM containing… read more here.
Keywords: architecture rank; pathology; myeloma; chromosomal architecture ... See more keywords