Principles of Chromosome Architecture Revealed by Hi-C.
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DOI: 10.1016/j.tibs.2018.03.006
Abstract: Chromosomes are folded and compacted in interphase nuclei, but the molecular basis of this folding is poorly understood. Chromosome conformation capture methods, such as Hi-C, combine chemical crosslinking of chromatin with fragmentation, DNA ligation, and… read more here.
Keywords: dna; cohesin; ctcf cohesin; principles chromosome ... See more keywords