Important roles of Vilse in dendritic architecture and synaptic plasticity
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DOI: 10.1038/srep45646
Abstract: Vilse/Arhgap39 is a Rho GTPase activating protein (RhoGAP) and utilizes its WW domain to regulate Rac/Cdc42-dependent morphogenesis in Drosophila and murine hippocampal neurons. However, the function of Vilse in mammalian dendrite architecture and synaptic plasticity… read more here.
Keywords: mice; architecture synaptic; synaptic plasticity; plasticity ... See more keywords
Nanoscale architecture of synaptic vesicles and scaffolding complexes revealed by cryo-electron tomography
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2403136121
Abstract: Significance Imaging the ultrastructure and molecular architecture of synapses is essential to understanding synaptic neurotransmission. Scaffolding proteins on both sides of the synapse form subsynaptic clusters that are aligned across the synapse. This is thought… read more here.
Keywords: architecture synaptic; synaptic vesicles; scaffolding complexes; tomography ... See more keywords