Genome architecture and totipotency: An intertwined relation during early embryonic development
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DOI: 10.1002/bies.202200029
Abstract: Chromosomes are not randomly packed and positioned into the nucleus but folded in higher‐order chromatin structures with defined functions. However, the genome of a fertilized embryo undergoes a dramatic epigenetic reprogramming characterized by extensive chromatin… read more here.
Keywords: development; architecture; chromatin; architecture totipotency ... See more keywords