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Analysis of proportional data in reproductive and developmental toxicity studies: Comparison of sensitivities of logit transformation, arcsine square root transformation, and nonparametric analysis

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Published in 2020 at "Birth Defects Research"

DOI: 10.1002/bdr2.1755

Abstract: In developmental and reproductive toxicity studies, analysis of litterā€based binary endpoints (e.g., incidence of malformed fetuses) is complex in that littermates often are not entirely independent of one another. It is well established that the… read more here.

Keywords: arcsine square; square root; analysis; transformation ... See more keywords