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   Articles with "arctiin" as a keyword



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Arctiin Prevents LPS-Induced Acute Lung Injury via Inhibition of PI3K/AKT Signaling Pathway in Mice

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recommendations! Published in 2018 at "Inflammation"

DOI: 10.1007/s10753-018-0856-x

Abstract: Arctiin is a lignin isolated from Arctium lappa which has been known to have anti-viral and anti-inflammatory effects. The aim of this study is to explore the protective effect of arctiin on lipopolysaccharide (LPS)-induced inflammatory… read more here.

Keywords: lps induced; arctiin; pi3k akt; signaling pathway ... See more keywords
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Anti-depressive effect of arctiin by attenuating neuroinflammation via HMGB1/TLR4- and TNF-α/TNFR1-mediated NF-κB activation.

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recommendations! Published in 2020 at "ACS chemical neuroscience"

DOI: 10.1021/acschemneuro.0c00120

Abstract: Inflammation is a potential factor in the pathophysiology of depression. A traditional Chinese herbal medicine, arctiin, and its aglycone, arctigenin, are the major bioactive components in Fructus arctii and exhibit neuroprotective and anti-inflammatory activities. Arctigenin… read more here.

Keywords: arctiin; tnf; activation; via hmgb1 ... See more keywords
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Synthesis, Structural Elucidation, and Anti-Inflammatory Activity of a Water-Soluble Derivative of Arctiin

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recommendations! Published in 2023 at "Molecules"

DOI: 10.3390/molecules28041789

Abstract: The poor oral bioavailability of arctiin caused by its low water solubility is the biggest obstacle in developing it as a drug. In this work, a new water-soluble glucuronide derivative of arctiin (arctigenin-4′-O-glucuronide) was synthesized… read more here.

Keywords: derivative arctiin; water; anti inflammatory; inflammatory activity ... See more keywords
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Arctiin regulates collagen type 1α chain 1 mRNA expression in human dermal fibroblasts via the miR‑378b‑SIRT6 axis.

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recommendations! Published in 2017 at "Molecular medicine reports"

DOI: 10.3892/mmr.2017.7679

Abstract: Arctiin, a lignin isolated from Arctium lappa, exhibits a variety of biological effects, including anti‑viral, anti‑inflammatory, and anti‑proliferative actions, in mammalian cells. In a previous study, arctiin was demonstrated to induce procollagen type I synthesis and… read more here.

Keywords: arctiin; mir 378b; expression; type ... See more keywords