Comparison of the predictive value of area under the curve versus maximum serum concentration of intravenous tobramycin in cystic fibrosis patients treated for an acute pulmonary exacerbation
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.25569
Abstract: The primary objective of this study was to compare the therapeutic predictive value of area under the curve (AUC24) versus maximum concentration (Cmax) in cystic fibrosis (CF) patients receiving intravenous (IV) tobramycin for a Pseudomonas… read more here.
Keywords: cystic fibrosis; value area; fibrosis patients; area curve ... See more keywords
Retrospective review of vancomycin monitoring via trough only versus two‐point estimated area under the curve in pediatric and adult patients with cystic fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.26190
Abstract: The primary objective of this study was to compare the occurrence of acute kidney injury (AKI) in patients with cystic fibrosis (CF) receiving intravenous (IV) vancomycin monitored through single serum trough concentrations and two‐point estimated… read more here.
Keywords: estimated area; patients cystic; two point; point estimated ... See more keywords
Combined phaco-vitrectomy provides lower costs and greater area under the curve vision gains than sequential vitrectomy and phacoemulsification
Sign Up to like & getrecommendations! Published in 2020 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-020-04877-4
Abstract: Purpose A majority of phakic patients undergoing pars plana vitrectomy for epiretinal membrane or macular hole require subsequent cataract surgery within 1–2 years. Combined phaco-vitrectomy eliminates the need for a second surgery and may enable patients… read more here.
Keywords: surgery; combined phaco; vitrectomy; area curve ... See more keywords
Estimation of the area under a curve via several B-spline-based regression methods and applications
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biopharmaceutical Statistics"
DOI: 10.1080/10543406.2020.1730871
Abstract: ABSTRACT Estimating the area under a curve (AUC) is an important subject in many fields of medicine and science. The regression model using B-spline functions provides flexibility in curve fitting, making it suitable for AUC… read more here.
Keywords: area curve; auc estimation; regression;
Impact of longer term phosphorus control on cardiovascular mortality in hemodialysis patients using an area under the curve approach: results from the DOPPS
Sign Up to like & getrecommendations! Published in 2020 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfaa054
Abstract: Abstract Background Serial assessment of phosphorus is currently recommended by the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines, but its additional value versus a single measurement is uncertain. Methods We studied data from 17 414 HD… read more here.
Keywords: mortality; phosphorus; area curve; auc ... See more keywords
Association Between Vancomycin Area Under the Curve and Nephrotoxicity: a single center, retrospective cohort study in a veteran population.
Sign Up to like & getrecommendations! Published in 2021 at "Open forum infectious diseases"
DOI: 10.1093/ofid/ofab094
Abstract: Background It is unclear which vancomycin area under the curve (AUC) values are most associated with risk for acute kidney injury (AKI). Methods This retrospective cohort study was undertaken to determine if vancomycin AUC >550 is… read more here.
Keywords: retrospective cohort; area curve; vancomycin area; auc 550 ... See more keywords
In Outpatients Receiving Parenteral Vancomycin, Dosing Adjustments Produced by Area Under the Curve-Based and Trough-Based Monitoring Differ Only at the Extremes of the Therapeutic Trough Range
Sign Up to like & getrecommendations! Published in 2023 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofac696
Abstract: Abstract Area under the curve (AUC)-based vancomycin dosing reduces nephrotoxicity but is burdensome. Reviewing 115 adults receiving ≥2 weeks of outpatient vancomycin, we found AUC-based and trough-based dose adjustments discordant only for troughs 16 mg/L. Selective… read more here.
Keywords: vancomycin; vancomycin dosing; based trough; trough based ... See more keywords
Vancomycin Area Under the Curve Simplified
Sign Up to like & getrecommendations! Published in 2018 at "Therapeutic Drug Monitoring"
DOI: 10.1097/ftd.0000000000000500
Abstract: Background: Serum trough concentrations as the sole means of monitoring safety and efficacy of vancomycin are insufficient. The daily area under the curve (AUC24) of serum concentration versus time to minimum inhibitory concentration (MIC) ratio… read more here.
Keywords: area curve; auc24; vancomycin area; greater 400 ... See more keywords
Can the Area Under the Curve/Trough Level Ratio Be Used to Optimize Tacrolimus Individual Dose Adjustment?
Sign Up to like & getrecommendations! Published in 2022 at "Transplantation"
DOI: 10.1097/tp.0000000000004405
Abstract: Background. The aim of this work was to evaluate, in a large data set of renal transplant recipients, the intraindividual variability of the area under the curve (AUC)/predose concentration (C0) ratio in comparison with that… read more here.
Keywords: auc; ratio; auc ratio; area curve ... See more keywords
"Quadripolar" Transcranial Electrical Stimulation for Motor Evoked Potentials.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Neurophysiology"
DOI: 10.1097/wnp.0000000000000751
Abstract: PURPOSE To determine if transcranial electrical stimulation (TES)-induced motor evoked potentials (MEPs) are of higher amplitude when using two electrodes as anodes and two as cathodes, known as "quadripolar stimulation." METHODS Patients who underwent TES… read more here.
Keywords: stimulation; area curve; electrical stimulation; evoked potentials ... See more keywords
Comparison of glucose time in range and area under curve in range in relation to risk of diabetic retinopathy in type 2 diabetes patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Diabetes Investigation"
DOI: 10.1111/jdi.13811
Abstract: We proposed a novel continuous glucose monitoring (CGM)‐based metric, area under the curve in range (AucIR), for integrating both the amplitude and duration of dysglycemia, and further compared AucIR with the emerging key CGM‐derived metric,… read more here.
Keywords: time range; curve range; range; area curve ... See more keywords