PEGylated Liposomes Accumulate in the Areas Relevant to Skin Toxicities via Passive Extravasation across "Leaky" Endothelium.
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DOI: 10.1021/acsnano.2c00423
Abstract: PEGylated liposome is the cornerstone platform for modern drug delivery. Unfortunately, as exemplified by PEGylated liposomal doxorubicin (aka Doxil), altered doxorubicin pharmacokinetics causes off-target accumulation in the skin, including the palms and feet, leading to… read more here.
Keywords: microscopy; skin toxicities; areas relevant; extravasation ... See more keywords