MYO1B as a prognostic biomarker and a therapeutic target in Arecoline-associated oral carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular carcinogenesis"
DOI: 10.1002/mc.23535
Abstract: BACKGROUND Arecoline, the main component of betel nut, induces malignant transformation of oral cells through complicated unclear mechanisms. Thus, we aimed to screen the key genes involved in Arecoline-induced oral cancer and further verify their… read more here.
Keywords: oral cancer; arecoline; therapeutic target; key gene ... See more keywords
Taiwanin C elicits apoptosis in arecoline and 4‐nitroquinoline‐1‐oxide‐induced oral squamous cell carcinoma cells and hinders proliferation via epidermal growth factor receptor/PI3K suppression
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22742
Abstract: Oral Squamous Cell Carcinoma (OSSC) is a major life‐threatening disease with high incidence in the Southeast Asian countries. Chronic exposure to arecoline causes genetic changes in the epithelial cells of the oral mucosa, induces proliferation… read more here.
Keywords: arecoline; oral squamous; squamous cell; cell carcinoma ... See more keywords
Arecoline activates latent transforming growth factor β1 via mitochondrial reactive oxygen species in buccal fibroblasts: Suppression by epigallocatechin-3-gallate.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2017.07.003
Abstract: BACKGROUND/PURPOSE Oral submucous fibrosis (OSF) is a premalignant condition caused by the chewing of areca nut (AN). Transforming growth factor β (TGFβ) plays a central role in the pathogenesis of OSF. Connective tissue growth factor… read more here.
Keywords: growth factor; arecoline; tgf; arecoline induced ... See more keywords
DARK Classics in Chemical Neuroscience: Arecoline.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.8b00711
Abstract: Arecoline is a naturally occurring psychoactive alkaloid from areca (betel) nuts of the areca palm ( Areca catechu) endemic to South and Southeast Asia. A partial agonist of nicotinic and muscarinic acetylcholine receptors, arecoline evokes… read more here.
Keywords: dark classics; arecoline; neuroscience arecoline; chemical neuroscience ... See more keywords
Taiwanin E Induces Cell Cycle Arrest and Apoptosis in Arecoline/4-NQO-Induced Oral Cancer Cells Through Modulation of the ERK Signaling Pathway
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.01309
Abstract: Taiwanin E is a bioactive compound extracted from Taiwania cryptomerioides Hayata. In this research endeavor, we studied the anti-cancer effect of Taiwanin E against arecoline and 4-nitroquinoline-1-oxide-induced oral squamous cancer cells (OSCC), and elucidated the… read more here.
Keywords: oral cancer; arecoline; induced oral; cancer cells ... See more keywords