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Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11850
Abstract: Arecoline, a major alkaloid of the areca nut, has potential toxicity to the nervous system. Our previous study reveals that the neurotoxicity of arecoline involves in inhibited endogenous hydrogen sulfide (H2S) generation. Therefore, the present…
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Keywords:
signaling pathway;
arecoline induced;
leptin receptor;
receptor signaling ... See more keywords
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Published in 2018 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2017.07.003
Abstract: BACKGROUND/PURPOSE Oral submucous fibrosis (OSF) is a premalignant condition caused by the chewing of areca nut (AN). Transforming growth factor β (TGFβ) plays a central role in the pathogenesis of OSF. Connective tissue growth factor…
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Keywords:
growth factor;
arecoline;
tgf;
arecoline induced ... See more keywords
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Published in 2021 at "Oncotarget"
DOI: 10.18632/oncotarget.28026
Abstract: Head and neck cancers are highly prevalent in south-east Asia, primarily due to betel nut chewing. Arecoline, the primary alkaloid is highly carcinogenic; however its role in promoting tumorigenesis by disrupting junctional complexes and increasing…
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Keywords:
jund;
disruption;
arecoline induced;
expression ... See more keywords