Abstract 5829: Elucidating the significance of amphiregulin and its implications for EGFR inhibition strategies in LKB1-mutant NSCLC
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DOI: 10.1158/1538-7445.am2024-5829
Abstract: LKB1-mutant non-small cell lung cancer (NSCLC) is aggressive and treatment-refractory, underscoring the need for new therapeutic strategies. Our comparative study involving mouse lung tumors driven by oncogenic KrasG12D and LKB1 loss as well as tumors… read more here.
Keywords: lung cancer; cancer; areg expression; lung ... See more keywords
Triiodothyronine (T3) increases the expression of the amphiregulin (AREG) oncogene by activating extranuclear pathways in MCF-7 breast cancer cells
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DOI: 10.20945/2359-4292-2023-0094
Abstract: ABSTRACT Objective: Considering that the αvβ3 integrin plays an important role in tumor metastasis, this study investigated the involvement of these pathways in mediating the triiodothyronine (T3) effects on amphiregulin (AREG) expression. Materials and methods:… read more here.
Keywords: triiodothyronine increases; expression amphiregulin; amphiregulin areg; areg expression ... See more keywords