Catalytic Electrophilic Halogenation of Arenes with Electron-Withdrawing Substituents.
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DOI: 10.1021/jacs.2c06440
Abstract: The electrophilic halogenation of arenes is perhaps the simplest method to prepare aryl halides, which are important structural motifs in agrochemicals, materials, and pharmaceuticals. However, the nucleophilicity of arenes is weakened by the electron-withdrawing substituents,… read more here.
Keywords: electron withdrawing; halogenation arenes; halogenation; arenes electron ... See more keywords