Synthesis of Arenesulfonyl Fluorides via Sulfuryl Fluoride Incorporation from Arynes.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.8b03610
Abstract: Transition-metal-free multicomponent reactions involving aryne precursors, secondary amines, and sulfuryl fluoride are reported herein. Zwitterionic intermediates formed from the reaction of arynes with amine nucleophiles can capture SO2F2 under mild conditions, offering a novel and… read more here.
Keywords: fluorides via; synthesis arenesulfonyl; via sulfuryl; fluoride incorporation ... See more keywords
Directed ortho-Metalation of Arenesulfonyl Fluorides and Aryl Fluorosulfates
Sign Up to like & getrecommendations! Published in 2019 at "Synthesis"
DOI: 10.1055/s-0037-1610877
Abstract: Studies on directed ortho-metalation (DoM) of arenesulfonyl fluorides (ArSO2F) with in situ electrophile trapping are presented. Under optimized conditions (LDA, THF, –78 °C), a series of model substrates was mono- and difunctionalized with trimethylsilyl chloride… read more here.
Keywords: aryl fluorosulfates; metalation; ortho metalation; directed ortho ... See more keywords