Marine antimicrobial peptide arenicin adopts a monomeric twisted β‐hairpin structure and forms low conductivity pores in zwitterionic lipid bilayers
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DOI: 10.1002/bip.23093
Abstract: Arenicins are 21‐residue β‐hairpin antimicrobial peptides (AMPs) isolated from the marine lugworm Arenicola marina [Ovchinnikova et al., FEBS Lett. 2004;577:209–214]. The peptides have a high positive charge (+6) and display a broad spectrum of antimicrobial… read more here.
Keywords: twisted hairpin; low conductivity; hairpin structure; arenicin ... See more keywords
Deleting the first disulphide bond in an arenicin derivative enhances its expression in Pichia pastoris
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DOI: 10.1111/lam.12770
Abstract: The marine antimicrobial peptide NZ17074, a variant of arenicin‐3 from Arenicola marina that has broad antimicrobial activity and high bioavailability, can be designed to treat bacterial and fungal diseases. To reduce the toxicity of NZ17074,… read more here.
Keywords: disulphide bond; antimicrobial activity; first disulphide; arenicin ... See more keywords