Activation of Nrf2/AREs-mediated antioxidant signalling, and suppression of profibrotic TGF-β1/Smad3 pathway: A promising therapeutic strategy for hepatic fibrosis - A review.
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DOI: 10.1016/j.lfs.2020.117909
Abstract: Hepatic fibrosis (HF) is a wound-healing response that occurs during chronic liver injury and features by an excessive accumulation of extracellular matrix (ECM) components. Activation of hepatic stellate cell (HSC), the leading effector in HF,… read more here.
Keywords: nrf2 ares; pathway; activation nrf2; tgf ... See more keywords