Upregulation of 5′-terminal oligopyrimidine mRNA translation upon loss of the ARF tumor suppressor
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-79379-8
Abstract: Tumor cells require nominal increases in protein synthesis in order to maintain high proliferation rates. As such, tumor cells must acquire enhanced ribosome production. How the numerous mutations in tumor cells ultimately achieve this aberrant… read more here.
Keywords: arf; oligopyrimidine mrna; mrna translation; translation ... See more keywords
Laser irradiation modulating the acoustic radiation force acting on a liquid ball in a plane progressive wave
Sign Up to like & getrecommendations! Published in 2019 at "AIP Advances"
DOI: 10.1063/1.5090408
Abstract: We present a theoretical study of the modulation using laser irradiation of an acoustic radiation force (ARF) acting on a liquid ball. The ARFs acting on a laser-irradiated oleic acid (OA) sphere were investigated using… read more here.
Keywords: arf; laser; liquid; acoustic radiation ... See more keywords
ARF Confers a Context-Dependent Response to Chemotherapy in Muscle-Invasive Bladder Cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer research"
DOI: 10.1158/0008-5472.can-16-2621
Abstract: Muscle-invasive bladder cancer (MIBC) generally responds poorly to treatment and tends to exhibit significant mortality. Here we show that expression of the tumor suppressor p14ARF (ARF) is upregulated in aggressive subtypes of MIBC. Accumulation of… read more here.
Keywords: chemotherapy; arf; bladder cancer; response ... See more keywords
Identification of De Novo Enhancers Activated by TGFβ to Drive Expression of CDKN2A and B in HeLa Cells
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Research"
DOI: 10.1158/1541-7786.mcr-19-0289
Abstract: Disruption of the CDKN2A (INK4A/ARF) and B (INK4B) genes, which encode three function-independent tumor suppressors, is one of the most common events in human cancer. Because their relative importance in tumor prevention appears to be… read more here.
Keywords: expression; arf; tgf; hela cells ... See more keywords
Is Inflammasome a Potential Target of Prophylaxis in Rheumatic Heart Disease?
Sign Up to like & getrecommendations! Published in 2018 at "Circulation"
DOI: 10.1161/circulationaha.118.036771
Abstract: Acute rheumatic fever (ARF) is a consequence of an autoimmune response to infection with the Gram-positive bacteria Streptococcus pyogenes or group A Streptococcus (GAS).1 ARF afflicts ≈.5 million people every year, and both environmental and… read more here.
Keywords: arf; gas; rheumatic heart; rhd ... See more keywords
Sexually dimorphic tumor suppression by small mitochondrial Arf
Sign Up to like & getrecommendations! Published in 2019 at "Oncotarget"
DOI: 10.18632/oncotarget.26651
Abstract: Internal translational initiation of the mRNA encoding the Arf tumor suppressor yields an N-terminally truncated small Arf protein (smArf) that lacks amino acid residues required for Mdm2 binding and p53 activation. Here, we report that… read more here.
Keywords: arf; dimorphic tumor; tumor suppression; sexually dimorphic ... See more keywords
GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.9957
Abstract: The alternative reading frame protein (p14ARF/ARF) is a key determinant of cell fate, acting as a potent tumor suppressor through a p53/MDM2-dependent pathway or promoting apoptosis in a p53-independent manner. The ARF protein is mainly… read more here.
Keywords: nucleolar arf; arf; degradation; protein ... See more keywords
Genome-Wide Identification and Co-Expression Analysis of ARF and IAA Family Genes in Euscaphis konishii: Potential Regulators of Triterpenoids and Anthocyanin Biosynthesis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.737293
Abstract: Euscaphis konishii is an evergreen plant that is widely planted as an industrial crop in Southern China. It produces red fruits with abundant secondary metabolites, giving E. konishii high medicinal and ornamental value. Auxin signaling… read more here.
Keywords: expression; ekarf genes; potential regulators; euscaphis konishii ... See more keywords
Evaluation of a Community-Led Program for Primordial and Primary Prevention of Rheumatic Fever in Remote Northern Australia
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph191610215
Abstract: Environmental factors including household crowding and inadequate washing facilities underpin recurrent streptococcal infections in childhood that cause acute rheumatic fever (ARF) and subsequent rheumatic heart disease (RHD). No community-based ‘primordial’-level interventions to reduce streptococcal infection… read more here.
Keywords: year; prevention; rheumatic fever; arf ... See more keywords
Non-invasive mechanical ventilation with average volume-assured pressure support. Results according to the aetiology of acute respiratory failure.
Sign Up to like & getrecommendations! Published in 2021 at "Anaesthesiology intensive therapy"
DOI: 10.5114/ait.2021.111527
Abstract: INTRODUCTION Until now, the ventilatory strategy with BiPAP S/T plus average volume-assured pressure support (AVAPS) has not been evaluated for its use in the different types of acute respiratory failure (ARF). Consequently we report the… read more here.
Keywords: volume assured; assured pressure; failure; acute respiratory ... See more keywords