Cdkn2a (Arf) loss drives NF1-associated atypical neurofibroma and malignant transformation.
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DOI: 10.1093/hmg/ddz095
Abstract: Plexiform neurofibroma (PN) tumors are a hallmark manifestation of neurofibromatosis type 1 (NF1) that arise in the Schwann cell (SC) lineage. NF1 is a common heritable cancer predisposition syndrome caused by germline mutations in the… read more here.
Keywords: arf loss; annubp; loss drives; neurofibroma ... See more keywords