L-Arg-Rich Amphiphilic Dendritic Peptide as a Versatile NO Donor for NO/Photodynamic Synergistic Treatment of Bacterial Infections and Promoting Wound Healing.
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DOI: 10.1002/smll.202101495
Abstract: The development of alternative strategies for the efficient treatment of subcutaneous abscesses that do not require the massive use of antibiotics and surgical intervention is urgently needed. Herein, a novel synergistic antibacterial strategy based on… read more here.
Keywords: versatile donor; arg; treatment; rich amphiphilic ... See more keywords
Middle-down proteomics reveals dense sites of methylation and phosphorylation in arginine-rich RNA-binding proteins.
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DOI: 10.1021/acs.jproteome.9b00633
Abstract: Post-translational modifications (PTMs) within arginine (Arg)-rich RNA-binding proteins, such as phosphorylation and methylation, regulate multiple steps in RNA metabolism. However, the identification of PTMs within Arg-rich domains with complete trypsin digestion is extremely challenging due… read more here.
Keywords: methylation; binding proteins; rna binding; arg rich ... See more keywords
Rational Framework for the Design of Trp- and Arg-Rich Peptide Antibiotics Against Multidrug-Resistant Bacteria
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.889791
Abstract: The threat of antibiotic resistance warrants the discovery of agents with novel antimicrobial mechanisms. Antimicrobial peptides (AMPs) directly disrupting bacterial membranes may overcome resistance to traditional antibiotics. AMP development for clinical use has been mostly… read more here.
Keywords: trp arg; multidrug resistant; arg rich; resistant bacteria ... See more keywords