DosR Regulates the Transcription of the Arginine Biosynthesis Gene Cluster by Binding to the Regulatory Sequences in Mycobacterium bovis Bacille Calmette-Guerin.
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DOI: 10.1089/dna.2022.0282
Abstract: l-Arginine serves as a carbon and nitrogen source and is critical for Mycobacterium tuberculosis (Mtb) survival in the host. Generally, ArgR acts as a repressor regulating arginine biosynthesis by binding to the promoter of the… read more here.
Keywords: mycobacterium bovis; arginine biosynthesis; mycobacterium; bacille calmette ... See more keywords
Catabolic Ornithine Carbamoyltransferase Activity Facilitates Growth of Staphylococcus aureus in Defined Medium Lacking Glucose and Arginine
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DOI: 10.1128/mbio.00395-22
Abstract: Staphylococcus aureus can cause infection in virtually any niche of the human host, suggesting that it has significant metabolic versatility. Indeed, bioinformatic analysis suggests that it has the biosynthetic capability to synthesize all 20 amino… read more here.
Keywords: growth; arginine biosynthesis; staphylococcus aureus; ornithine carbamoyltransferase ... See more keywords
The Arginine Biosynthesis Pathway of Candida albicans Regulates Its Cross-Kingdom Interaction with Actinomyces viscosus to Promote Root Caries
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DOI: 10.1128/spectrum.00782-22
Abstract: Root caries is a critical problem that threatens the oral health of the elderly population. Our results identified the essential roles of the C. albicans arginine biosynthesis pathway in its cross-kingdom interactions with A. viscosus… read more here.
Keywords: biosynthesis pathway; root; root caries; arginine biosynthesis ... See more keywords
Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis.
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DOI: 10.7554/elife.81289
Abstract: Nutrient stress in the tumor microenvironment requires cancer cells to adopt adaptive metabolic programs for survival and proliferation. Therefore, knowledge of microenvironmental nutrient levels and how cancer cells cope with such nutrition is critical to… read more here.
Keywords: stress; cell; arginine biosynthesis; amino acid ... See more keywords