Effect of toothpaste containing arginine on dental plaque-A randomized controlled in situ study.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of dentistry"
DOI: 10.1016/j.jdent.2017.10.001
Abstract: OBJECTIVES To evaluate the effects of 8% arginine-containing toothpaste on the dental plaque of no caries (NC) and high caries (HC) individuals in situ. METHODS 6 no caries (DMFT=0) and 6 high caries (DMFT≥6) individuals… read more here.
Keywords: study; arginine containing; dental plaque; situ ... See more keywords
Nuclear localized C9orf72-associated arginine-containing dipeptides exhibit age-dependent toxicity in C. elegans
Sign Up to like & getrecommendations! Published in 2017 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddx372
Abstract: Abstract A hexanucleotide repeat expansion mutation in the C9orf72 gene represents a prevalent genetic cause of several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Non-canonical translation of this repeat gives rise to… read more here.
Keywords: toxicity elegans; age; containing dipeptides; arginine containing ... See more keywords
Arginine-Containing Tripeptides as Analgesic Substances: The Possible Mechanism of Ligand-Receptor Binding to the Slow Sodium Channel
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23115993
Abstract: Two short arginine-containing tripeptides, H-Arg-Arg-Arg-OH (TP1) and Ac-Arg-Arg-Arg-NH2 (TP2), have been shown by the patch-clamp method to modulate the NaV1.8 channels of DRG primary sensory neurons, which are responsible for the generation of nociceptive signals.… read more here.
Keywords: receptor binding; ligand receptor; containing tripeptides; arg arg ... See more keywords
Role of the Guanidinium Groups in Ligand–Receptor Binding of Arginine-Containing Short Peptides to the Slow Sodium Channel: Quantitative Approach to Drug Design of Peptide Analgesics
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810640
Abstract: Several arginine-containing short peptides have been shown by the patch-clamp method to effectively modulate the NaV1.8 channel activation gating system, which makes them promising candidates for the role of a novel analgesic medicinal substance. As… read more here.
Keywords: short peptides; ligand receptor; guanidinium groups; containing short ... See more keywords
Discovery of arginine-containing tripeptides as a new class of pancreatic lipase inhibitors.
Sign Up to like & getrecommendations! Published in 2019 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2018-0216
Abstract: AIM The inhibition of pancreatic lipase (PL) represents one of the most promising strategies in the search for novel antiobesity drugs. We propose here a pioneering course by exploring tripeptide scaffolds in the way to… read more here.
Keywords: pancreatic lipase; tripeptides new; arginine containing; lipase ... See more keywords