Preferential interactions of trehalose, L-arginine.HCl and sodium chloride with therapeutically relevant IgG1 monoclonal antibodies
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DOI: 10.1080/19420862.2017.1358328
Abstract: ABSTRACT Preferential interactions of weakly interacting formulation excipients govern their effect on the equilibrium and kinetics of several reactions of protein molecules in solution. Using vapor pressure osmometry, we characterized the preferential interactions of commonly… read more here.
Keywords: monoclonal antibodies; arginine hcl; preferential interactions; igg1 monoclonal ... See more keywords