Arginine limitation drives a directed codon-dependent DNA sequence evolution response in colorectal cancer cells
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DOI: 10.1126/sciadv.ade9120
Abstract: Utilization of specific codons varies between organisms. Cancer represents a model for understanding DNA sequence evolution and could reveal causal factors underlying codon evolution. We found that across human cancer, arginine codons are frequently mutated… read more here.
Keywords: sequence evolution; dna sequence; arginine limitation; cancer ... See more keywords