Prostate-specific membrane antigen modulates the progression of prostate cancer by regulating the synthesis of arginine and proline and the expression of androgen receptors and Fos proto-oncogenes
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2016086
Abstract: ABSTRACT The expression of prostate-specific membrane antigen (PSMA) is strikingly upregulated during oncogenesis and prostate cancer (PCa) progression, but the functions of this antigen in PCa remain unclear. Here, we constructed PSMA-knockdown LNCaP and 22rv1… read more here.
Keywords: arginine proline; prostate specific; pca; expression ... See more keywords
Staphylococcus aureus Does Not Synthesize Arginine from Proline under Physiological Conditions
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DOI: 10.1128/jb.00018-22
Abstract: Staphylococcus aureus is a versatile Gram-positive human pathogen infecting various human organs. The bacterium's versatility is partly due to efficient metabolic regulation via the carbon catabolite repression system (CCR). S. aureus is known to interconvert… read more here.
Keywords: synthesize arginine; arginine; staphylococcus aureus; proline ... See more keywords
Abstract 280: ALDH2 knockout dysregulates arginine and proline metabolism in SK-BR-3 breast cancer cells
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DOI: 10.1158/1538-7445.am2025-280
Abstract: Aldehyde dehydrogenase 2 (ALDH2) mitigates cellular stress by detoxifying reactive aldehydes produced during alcohol exposure and endogenous metabolic processes. The ALDH2*2 variant, prevalent in East Asian populations, has decreased catalytic activity, which is linked to… read more here.
Keywords: proline metabolism; cancer; metabolism; arginine proline ... See more keywords
Novel Arginine- and Proline-Rich Candidacidal Peptides Obtained through a Bioinformatic Approach
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DOI: 10.3390/antibiotics12030472
Abstract: Antimicrobial resistance is a major public health concern worldwide. Albeit to a lesser extent than bacteria, fungi are also becoming increasingly resistant to antifungal drugs. Moreover, due to the small number of antifungal classes, therapy… read more here.
Keywords: proline rich; bioinformatic approach; proline; arginine proline ... See more keywords