Novel Serine-Arginine Protein Kinase Inhibitors for Treating Cancer.
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DOI: 10.1021/acsmedchemlett.3c00132
Abstract: Described herein are novel serine-arginine protein kinase (SRPK) inhibitors, their pharmaceutical compositions, the use of such compounds in treating cancer, and processes for preparing such compounds. read more here.
Keywords: protein kinase; serine arginine; treating cancer; arginine protein ... See more keywords
Impaired expression of serine/arginine protein kinase 2 (SRPK2) affects melanoma progression
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DOI: 10.3389/fgene.2022.979735
Abstract: Melanoma is one of the most aggressive tumors, and its lethality is associated with the ability of malignant cells to migrate and invade surrounding tissues to colonize distant organs and to generate widespread metastasis. The… read more here.
Keywords: melanoma; progression; serine arginine; melanoma progression ... See more keywords
Knockdown of Serine–Arginine Protein Kinase 1 Inhibits the Growth and Migration in Renal Cell Carcinoma Cells
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DOI: 10.3727/096504016x14743324568129
Abstract: The pre-mRNA splicing regulator serine–arginine protein kinase 1 (SRPK1), a member of the SR kinase family, plays an essential role in cancer development and various pathophysiological processes. However, its expression pattern and functions in renal… read more here.
Keywords: renal cell; serine arginine; rcc; protein kinase ... See more keywords