Structural Foundations of RNA Silencing by Argonaute.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2017.07.018
Abstract: Nearly every cell in the human body contains a set of programmable gene-silencing proteins named Argonaute. Argonaute proteins mediate gene regulation by small RNAs and thereby contribute to cellular homeostasis during diverse physiological process, such… read more here.
Keywords: foundations rna; rna silencing; silencing argonaute; argonaute proteins ... See more keywords
The prokaryotic Argonaute proteins enhance homology sequence-directed recombination in bacteria
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz040
Abstract: Abstract Argonaute proteins are present and conserved in all domains of life. Recently characterized prokaryotic Argonaute proteins (pAgos) participates in host defense by DNA interference. Here, we report that the Natronobacterium gregoryi Argonaute (NgAgo) enhances… read more here.
Keywords: proteins enhance; prokaryotic argonaute; argonaute; enhance homology ... See more keywords
A comprehensive survey of C. elegans argonaute proteins reveals organism-wide gene regulatory networks and functions
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.08.08.502013
Abstract: Argonaute (AGO) proteins associate with small RNAs to direct their effector function on complementary transcripts. The nematode C. elegans contains an expanded family of 19 functional AGO proteins, many of which have not been fully… read more here.
Keywords: argonaute proteins; elegans argonaute; proteins reveals; comprehensive survey ... See more keywords
Argonaute Proteins: From Structure to Function in Development and Pathological Cell Fate Determination
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2019.00360
Abstract: The highly conserved Argonaute protein family members play a central role in the regulation of gene expression networks, orchestrating the establishment and the maintenance of cell identity throughout the entire life cycle, as well as… read more here.
Keywords: early development; argonaute proteins; structure; function ... See more keywords
RNAi-Related Dicer and Argonaute Proteins Play Critical Roles for Meiocyte Formation, Chromosome-Axes Lengths and Crossover Patterning in the Fungus Sordaria macrospora
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.684108
Abstract: RNA interference (RNAi) is a cellular process involving small RNAs that target and regulate complementary RNA transcripts. This phenomenon has well-characterized roles in regulating gene and transposon expression. In addition, Dicer and Argonaute proteins, which… read more here.
Keywords: dicer argonaute; meiocyte formation; sordaria macrospora; formation ... See more keywords
Argonaute Proteins Take Center Stage in Cancers
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13040788
Abstract: Simple Summary The dysregulation of RNA interference (RNAi) has often been observed in cancers, where the main focus of research has been on the small RNA molecules directing RNAi. In this review, we focus on… read more here.
Keywords: stage cancers; proteins take; take center; center stage ... See more keywords