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Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity

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Published in 2018 at "Cell reports"

DOI: 10.1016/j.celrep.2018.10.097

Abstract: SUMMARY The epithelial-specific splicing regulators Esrp1 and Esrp2 are required for mammalian development, including establishment of epidermal barrier functions. However, the mechanisms by which Esrp ablation causes defects in epithelial barriers remain undefined. We determined… read more here.

Keywords: arhgef11; epithelial tight; tight junction; junction integrity ... See more keywords