Abstract LB044: Modeling the role of ARID1A in colon cancer using patient-derived organoids
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DOI: 10.1158/1538-7445.am2023-lb044
Abstract: Loss-of-function (LOF) mutations in genes encoding subunits of SWI/SNF chromatin remodeling complexes are found in approximately 25% of human cancers. Colorectal cancers (CRC), the second leading cause of cancer related deaths, are particularly vulnerable to… read more here.
Keywords: role arid1a; arid1a colon; arid1a; cancer ... See more keywords