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Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201700116
Abstract: In this study, surface molecularly imprinted polymers were prepared as the selective sorbents for separation of aristolochic acid I in herbal medicine extracts by a facile approach. A less toxic dummy template, ofloxacin, was used…
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Keywords:
extraction;
analysis;
molecularly imprinted;
acid ... See more keywords
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Published in 2019 at "Journal of separation science"
DOI: 10.1002/jssc.201900554
Abstract: Aristolochic acid I is a toxic compound found in the genus of Aristolochia plants, which are commonly used as herbal cough treatment medicines. To remove the aristolochic acid I in extract efficiently and selectively, a…
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Keywords:
ionic liquid;
molecular imprinted;
imprinted polymer;
polymer composited ... See more keywords
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Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113537
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Aristolochic acid nephropathy (AAN) is a kidney disease caused by the administration of plants containing aristolochic acids (AAs). Aristolochic acid I (AAI) is the main toxic component in AAs. Organic anion transporters (OATs)…
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Keywords:
tissue distribution;
pharmacokinetics tissue;
aai;
aai aaia ... See more keywords
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Published in 2020 at "Microchemical Journal"
DOI: 10.1016/j.microc.2019.104463
Abstract: Abstract Aristolochic acid I (AAI), which is naturally produced in aristolochiaceae plants, has aroused many attentions due to nephrotoxicity. Dummy molecularly imprinted silica (MIS) materials have been prepared and applied to selectively remove aristolochic acid…
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Keywords:
kaempfer dutchmanspipe;
root extract;
acid;
dutchmanspipe root ... See more keywords
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Published in 2019 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2019.04.014
Abstract: &NA; As the main toxic component of aristolochic acid, aristolochic acid I (AAI) is primarily found in Aristolochiaceae plants such as Aristolochia, Aristolochia fangchi and Caulis aristolochiae manshuriensis. AAI has been proven to be carcinogenic,…
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Keywords:
metabolism;
fatty acids;
testicular toxicity;
acid ... See more keywords
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Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-23565-2
Abstract: Experimental aristolochic acid nephropathy is characterized by transient acute proximal tubule necrosis and inflammatory cell infiltrates followed by interstitial fibrosis and tubular atrophy. The respective role of T-cell subpopulations has never been studied in the…
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Keywords:
cd4 cd8;
cd8 cells;
acid nephropathy;
depletion ... See more keywords
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Published in 2021 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2021.1946229
Abstract: Abstract Aristolochic acid (AA) are persistent soil pollutants in the agricultural fields of the Balkan Peninsula. Preparations containing aristolochic acid are widely used for anti-inflammatory, diuretic, etc. To study the hepatotoxicity of aristolochic acid, 80…
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Keywords:
blank group;
group;
aristolochic acid;
oxidative stress ... See more keywords
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Published in 2022 at "Toxicology research"
DOI: 10.1093/toxres/tfac002
Abstract: The aristolochic acids (AAs), derived from Aristolochia and Asarum species used widely in herbal medicines, are closely associated with liver cancer. The major AA derivatives are aristolochic acid I (AAI) and II (AAII), which can…
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Keywords:
liver cancer;
liver;
prognosis;
cancer patients ... See more keywords
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Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5731588
Abstract: Aristolochic acid (AA) ingestion causes Balkan nephropathy, characterized by tubular injury and progression to chronic kidney disease (CKD). AA is taken up by proximal tubule cells via organic anion transport (OAT3) and induces p53-mediated DNA…
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Keywords:
western diet;
kidney;
physiology;
aristolochic acid ... See more keywords
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Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.150723
Abstract: Aristolochic acid (AA) is the causative nephrotoxic alkaloid in AA nephropathy, which results in a tubulointerstitial fibrosis. AA causes direct proximal tubule damage as well as an influx of macrophages, although the role of macrophages…
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Keywords:
increased apoptosis;
aristolochic acid;
interferon regulatory;
migration ... See more keywords
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Published in 2017 at "Journal of the Brazilian Chemical Society"
DOI: 10.21577/0103-5053.20170059
Abstract: A new pyranone, (S)-2-(4-hydroxyphenylethyl)-6-methyl-2,3-dihydro-4H-pyran-4-one, with unusual carbon skeleton, and three new aristolochic acid derivatives (7-O-methylaristolochic acid F, sodium 7-O-methylaristolochate F and sodium aristolochate F) were isolated from Aristolochia urupaensis (Aristolochiaceae) stems together with 31 known…
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Keywords:
phenylethylpyranone aristolochic;
derivatives aristolochia;
acid derivatives;
aristolochia urupaensis ... See more keywords