Approaches for testing noninferiority in two-arm trials for risk ratio and odds ratio
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biopharmaceutical Statistics"
DOI: 10.1080/10543406.2019.1572616
Abstract: ABSTRACT For an existing established drug regimen, active control trials are defacto standard due to ethical reason as well as for clinical equipoise. However, when superiority claim of a new drug against the active control… read more here.
Keywords: two arm; arm trials; odds ratio; noninferiority ... See more keywords
New approaches for testing non-inferiority for three-arm trials with Poisson distributed outcomes.
Sign Up to like & getrecommendations! Published in 2020 at "Biostatistics"
DOI: 10.1093/biostatistics/kxaa014
Abstract: With the availability of limited resources, innovation for improved statistical method for the design and analysis of randomized controlled trials (RCTs) is of paramount importance for newer and better treatment discovery for any therapeutic area.… read more here.
Keywords: three arm; non inferiority; treatment; arm trials ... See more keywords