Cullin 3 targets the tumor suppressor gene ARMC5 for ubiquitination and degradation.
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DOI: 10.1530/erc-19-0502
Abstract: ARMC5 (Armadillo repeat containing 5) was identified as a new tumor suppressor gene responsible for hereditary adrenocortical tumors and meningiomas. ARMC5 is ubiquitously expressed and encodes a protein which contains a N-terminal Armadillo repeat domain… read more here.
Keywords: tumor suppressor; suppressor gene; armc5 ubiquitination; ubiquitination degradation ... See more keywords