ARNT deficiency represses pyruvate dehydrogenase kinase 1 to trigger ROS production and melanoma metastasis
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DOI: 10.1038/s41389-020-00299-3
Abstract: The metabolic changes in melanoma cells that are required for tumor metastasis have not been fully elucidated. In this study, we show that the increase in glucose uptake and mitochondrial oxidative phosphorylation confers metastatic ability… read more here.
Keywords: metastasis; dehydrogenase kinase; arnt deficiency; deficiency ... See more keywords