Pd-Catalyzed para-selective C-H difluoromethylation of aromatic carbonyls.
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DOI: 10.1039/c8cc09129c
Abstract: A novel palladium catalyzed highly para-selective C-H difluoromethylation of electron-deficient aromatic carbonyls was developed. Diverse substituted aromatic ketones and benzoates were selectively difluoromethylated at the remote para-site of carbonyl groups in moderate to good yields.… read more here.
Keywords: para selective; selective difluoromethylation; aromatic carbonyls; catalyzed para ... See more keywords