Electrochemically Driven Asymmetric Hydrogenation of Aromatic Ketones by Noyori–Ikariya Catalyst
Sign Up to like & getrecommendations! Published in 2024 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.7773
Abstract: The electrochemically driven asymmetric hydrogenation of 2,2,2‐trifluoroacetophenone was performed using a Noyori–Ikariya catalyst, yielding a 97% product yield and a 47% enantiomeric excess (ee) with a charge input of only 0.5 F/mol. In comparison, the ethoxylate… read more here.
Keywords: driven asymmetric; electrochemically driven; hydrogenation; noyori ikariya ... See more keywords
Unveiling the reaction process of the amine in direct amidation of aromatic ketones in H2O
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DOI: 10.1002/open.202000178
Abstract: Abstract In the classical amidation between aromatic ketones and amines, 2.0 equivalents of amines are necessarily required to gain satisfying yields. The specific role of the amine in the direct amidation already puzzled us for… read more here.
Keywords: aromatic ketones; amine direct; direct amidation; amine ... See more keywords
Experimental determination of thermodynamic properties of terpene and aromatic ketones by gas chromatography
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2020.114531
Abstract: Abstract The terpene and aromatic ketones are among oxygenated compounds present in essential oils (Eos). They are substances of great importance to the chemical, pharmaceutical, and the food industries. Because of their applications in these… read more here.
Keywords: thermodynamic properties; terpene aromatic; gas chromatography; aromatic ketones ... See more keywords
Palladium-catalyzed cross-coupling of aroyl chlorides with aryl stannanes in the presence of triethylsilane: Efficient access to aromatic ketones
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2020.152466
Abstract: Abstract Herein, we report the development of a palladium-catalyzed cross-coupling reaction that focuses on the preparation of aromatic ketones. Aroyl chlorides react quickly at 120 °C with aryl stannanes in the presence of Pd(PPh3)4 and Et3SiH… read more here.
Keywords: aryl stannanes; aromatic ketones; aroyl chlorides; palladium catalyzed ... See more keywords
Selective Oxidation of Alkylarenes to the Aromatic Ketones or Benzaldehydes with Water.
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DOI: 10.1021/acs.orglett.1c04154
Abstract: Here a palladium-catalyzed oxidation method for converting alkylarenes into the aromatic ketones or benzaldehydes with water as the only oxygen donor is reported. This C-H bond oxidation functionalization does not require other oxidants and hydrogen… read more here.
Keywords: oxidation; water; alkylarenes aromatic; ketones benzaldehydes ... See more keywords
Heteroaromatic swapping in aromatic ketones
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DOI: 10.1038/s41467-025-64041-6
Abstract: The modification of aromatic rings to heteroaromatic rings is a widely employed strategy in medicinal chemistry, often used to modulate lipophilicity and improve metabolic stability. However, achieving a one-step, generalizable transformation of aromatic rings into… read more here.
Keywords: chemistry; aromatic rings; rings heteroaromatic; heteroaromatic rings ... See more keywords
Highly efficient synthesis of chiral aromatic ketones via Rh-catalyzed asymmetric hydrogenation of β,β-disubstituted enones.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc04045h
Abstract: A succinct and efficient protocol was developed for the synthesis of chiral aromatic ketones via asymmetric hydrogenation of β,β-disubstituted enones with rhodium catalysts based on chiral bisphosphine thiourea ligands. A series of substrates (17 examples)… read more here.
Keywords: ketones via; aromatic ketones; synthesis chiral; asymmetric hydrogenation ... See more keywords
Iridium-catalyzed direct asymmetric reductive amination of aromatic ketones
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DOI: 10.1039/c7qo00400a
Abstract: The highly efficient direct catalytic reductive amination of aromatic ketones with diphenylmethanamine is described. Catalyzed by the iridium–monodentate phosphoramidite complex and assisted using additives, this concise and practical route provided chiral amines in high yields… read more here.
Keywords: amination aromatic; aromatic ketones; iridium catalyzed; reductive amination ... See more keywords
Direct Oxidative Dearomatization of Indoles with Aromatic Ketones: Rapid Access to 2,2-Disubstituted Indolin-3-ones
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DOI: 10.1055/s-0039-1691528
Abstract: A metal-free oxidative dearomatization of indoles with aromatic ketones mediated by TEMPO oxoammonium salt is described. The dearomatization proceeds smoothly and displays a broad substrate scope with respect to both indoles and aromatic ketones in… read more here.
Keywords: aromatic ketones; oxidative dearomatization; disubstituted indolin; indoles aromatic ... See more keywords
Developments in transfer hydrogenations of aromatic ketones catalyzed by boron compounds
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Coordination Chemistry"
DOI: 10.1080/00958972.2017.1300659
Abstract: Abstract Boron complexes BL1 and BL2 were prepared from O-donor ligands, 2,2′-(1E,1′E)-(ethane-1,2-diylbis(azan-1-yl-1-ylidene))bis(methane-1-yl-1-ylidene)diphenol (L1) and 2,2′-(propane-1,3-diylbis(azan-1-yl-1-ylidene))bis(methane-1-yl-1-ylidene)diphenol (L2). The complexes were fully characterized by 1H and 13C NMR, LC-MS/MS, TGA/DTA, UV-Vis, elemental analysis, SEM, and FTIR. The… read more here.
Keywords: developments transfer; aromatic ketones; ylidene; boron complexes ... See more keywords
Chiral Bifunctional Photocatalysts with Aromatic Ketones as Photosensitizers.
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DOI: 10.2533/chimia.2025.803
Abstract: Because the biological activity of a molecule is directly linked to its three-dimensional configuration, the preparation of chiral compounds is a central discipline in synthetic organic chemistry. With the exploitation of photoredox catalysis that gives… read more here.
Keywords: chemistry; ketones photosensitizers; photocatalysts aromatic; aromatic ketones ... See more keywords