Aromatic polyketides from a caterpillar associated Alternaria sp.
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.06.071
Abstract: Five new aromatic polyketides, alternaphenols A-E (1-5), and two known compounds (6-7) were isolated from a liquid culture of Alternaria sp. (strain no. NF2198), a caterpillar associated fungus. Their structures were determined by extensive spectroscopic… read more here.
Keywords: aromatic polyketides; associated alternaria; polyketides caterpillar; caterpillar associated ... See more keywords
Naphpyrones A-H, Antibacterial Aromatic Polyketides Isolated from the Streptomyces coelicolor A3(2)/spi1 ΔspiH3.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c09101
Abstract: Staphylococcus aureus, a common foodborne pathogen, has a close association with agriculture and food. With the rapid emergence and widespread dissemination of antimicrobial resistance, efforts have been directed toward developing and studying new antimicrobial compounds… read more here.
Keywords: food; spi1 spih3; streptomyces coelicolor; aromatic polyketides ... See more keywords
Aromatic Polyketides from the Mangrove-Derived Streptomyces sp. SCSIO 40069.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.2c01169
Abstract: A chemical investigation of Streptomyces sp. SCSIO 40069 resulted in the isolation of a series of aromatic polyketides with rare skeletons, including five new compounds RM18c-RM18g (1-5) and three known ones (6-8). Their structures and… read more here.
Keywords: streptomyces scsio; aromatic polyketides; mangrove derived; derived streptomyces ... See more keywords
Six Sets of Aromatic Polyketides Differing in Size and Shape Derive from a Single Biosynthetic Gene Cluster.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.3c00202
Abstract: One new aromatic polyketide, prealnumycin B (1), and four known aromatic polyketides, K1115A (2), 1,6-dihydroxy-8-propylanthraquinone (DHPA, 3), phaeochromycin B (4), and (R)-7-acetyl-3,6-dihydroxy-8-propyl-3,4dihydronaphthalen-1(2H)-one (5), were isolated from the marine-derived Streptomyces sundarbansensis SCSIO NS01; these compounds represent… read more here.
Keywords: differing size; aromatic polyketides; size shape; cluster ... See more keywords
Antibacterial Aromatic Polyketides Incorporating the Unusual Amino Acid Enduracididine.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.8b00354
Abstract: The increasing incidence of infections caused by drug-resistant pathogens requires new efforts for the discovery of novel antibiotics. By screening microbial extracts in an assay aimed at identifying compounds interfering with cell wall biosynthesis, based… read more here.
Keywords: aromatic polyketides; antibacterial aromatic; amino acid; acid enduracididine ... See more keywords
Metabolic Engineering and Synthetic Biology Approaches for the Heterologous Production of Aromatic Polyketides
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24108923
Abstract: Polyketides are a diverse set of natural products with versatile applications as pharmaceuticals, nutraceuticals, and cosmetics, to name a few. Of several types of polyketides, aromatic polyketides comprising type II and III polyketides contain many… read more here.
Keywords: metabolic engineering; aromatic polyketides; engineering synthetic; biology ... See more keywords
Discovery of Tricyclic Aromatic Polyketides Reveals Hidden Chain-Length Flexibility in Type II Polyketide Synthases
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms26167801
Abstract: Type II polyketide synthases (PKSs) collectively generate polyketide intermediates of varying chain lengths, which undergo cyclization and further tailoring to produce structurally diverse aromatic polyketides. The length of the polyketide chain is a critical factor… read more here.
Keywords: chain length; type; polyketide; aromatic polyketides ... See more keywords
Aromatic Polyketides from a Symbiotic Strain Aspergillus fumigatus D and Characterization of Their Biosynthetic Gene D8.t287
Sign Up to like & getrecommendations! Published in 2020 at "Marine Drugs"
DOI: 10.3390/md18060324
Abstract: The chemical investigation of one symbiotic strain, Aspergillus fumigatus D, from the coastal plant Edgeworthia chrysantha Lindl led to the isolation of eight compounds (1–8), which were respectively identified as rubrofusarin B (1), alternariol 9-O-methyl… read more here.
Keywords: aspergillus fumigatus; strain aspergillus; symbiotic strain; aromatic polyketides ... See more keywords
Aromatic Polyketides from the Deep-Sea Cold-Seep Mussel Associated Endozoic Fungus Talaromyces minioluteus CS-138
Sign Up to like & getrecommendations! Published in 2022 at "Marine Drugs"
DOI: 10.3390/md20080529
Abstract: Five new aromatic polyketides, including a unique benzofuran derivative, talarominine A (1), and four chromone analogs talamins A–D (2–5), along with one known related metabolite, 5-hydroxy-7-methoxy-2,3-dimethylchromone (6), were isolated and identified from the Talaromyces minioluteus… read more here.
Keywords: aromatic polyketides; deep sea; minioluteus 138; talaromyces minioluteus ... See more keywords