Chiral Squaramide Catalyzed Asymmetric Spiroketalization toward Aromatic [6,5] Spiroketals.
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DOI: 10.1021/acs.orglett.2c00074
Abstract: Herein is disclosed an efficient enantio- and diastereoselective spiroketalization of aromatic ketone tethered to ortho-homoformyl and enone moiety via in situ enol formation using quinine derived squaramide organocatalyst to access aromatic [6,5] spiroketals with complete… read more here.
Keywords: spiroketalization; asymmetric spiroketalization; aromatic spiroketals; catalyzed asymmetric ... See more keywords