Design, synthesis and biological evaluation of a novel library of antimitotic C2‐aroyl/arylimino tryptamine derivatives that are also potent inhibitors of indoleamine‐2, 3‐dioxygenase (IDO)
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.08.033
Abstract: ABSTRACT A novel library of C2‐substituted tryptamines (based on diverse C2‐aroyl/arylimino indoles and indole‐diketopiperazine hybrids) possessing antimitotic properties were designed, synthesized and screened for their inhibitory activity against tubulin polymerization, and against proliferation of A549… read more here.
Keywords: aroyl arylimino; hela; cancer; indoleamine dioxygenase ... See more keywords