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Published in 2021 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2021.691319
Abstract: Indoleamine-2,3-dioxygenase (IDO1) and tryptophan dioxygenases are two heme based metalloenzymes that catalyze the tryptophan oxidation reaction by inserting molecular dioxygen to cleave the pyrrole ring. The mechanism of such ring cleavage reaction is of carcinogenic…
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Keywords:
aroyl indoles;
mechanism;
mass spectroscopy;
spectroscopy ... See more keywords