A general approach to intermolecular carbonylation of arene C–H bonds to ketones through catalytic aroyl triflate formation
Sign Up to like & getrecommendations! Published in 2017 at "Nature Chemistry"
DOI: 10.1038/nchem.2903
Abstract: The development of metal-catalysed methods to functionalize inert C–H bonds has become a dominant research theme in the past decade as an approach to efficient synthesis. However, the incorporation of carbon monoxide into such reactions… read more here.
Keywords: general approach; aroyl triflate; approach intermolecular; arene bonds ... See more keywords
A Theoretical Study on Pd-catalyzed, Friedel-Crafts Intermolecular Acylation: Does Generated In Situ Aroyl Triflate Act as A Reactive Electrophile to Functionalize C–H Bond of Arenes?
Sign Up to like & getrecommendations! Published in 2019 at "Catalysts"
DOI: 10.3390/catal9020141
Abstract: The mechanism of Pd-catalyzed, Friedel-Crafts intermolecular acylation of arenes to ketones was comprehensively investigated by using DFT calculations. The calculated results revealed that this transformation was composed of several key steps: C–I bond oxidative addition,… read more here.
Keywords: friedel crafts; intermolecular acylation; crafts intermolecular; aroyl triflate ... See more keywords