Synthesis, antioxidant and antimicrobial activities of novel thiopyrano[2,3-d]thiazoles based on aroylacrylic acids
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Diversity"
DOI: 10.1007/s11030-017-9737-8
Abstract: Here it is described the synthesis, antioxidant and antimicrobial activity determination of novel rel-($$5R,6S,7R$$5R,6S,7R)-6-benzoyl-7-phenyl-2-oxo-3,5,6,7-tetrahydro-2H-thiopyrano[2,3-d]thiazole-5-carboxylic acids. The target compounds were obtained in good yields from 5-arylidene-4-thioxo-2-thiazolidinones and $$\upbeta $$β-aroylacrylic acids via regio- and diastereoselective hetero-Diels–Alder reaction.… read more here.
Keywords: antimicrobial activities; aroylacrylic acids; synthesis antioxidant; thiopyrano ... See more keywords
Synthesis of new structurally diverse thiazolidinone-derived compounds based on reaction of isorhodanine with ortho-substituted aldehydes, α-keto- and β-aroylacrylic acids
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DOI: 10.1016/j.molstruc.2020.128448
Abstract: Abstract Various novel structurally diverse thiazolidinone-derived compounds were synthesized from isorhodanine (4-thioxo-2-thiazolidinone) with ortho-substituted aldehydes, arylidene pyruvic and β-aroylacrylic acids. Michael reaction of isorhodanine with arylidene pyruvic and β-aroylacrylic acids providing 2-oxo-4-(2-oxo-4-thioxothiazolidin-5-yl)-4-phenylbutyric and 4-oxo-2-(2-oxo-2,3-dihydrothiazol-4-ylsulfanyl)-4-phenylbutyric acid… read more here.
Keywords: aroylacrylic acids; thiazolidinone derived; thiazolidinone; structurally diverse ... See more keywords
Synthesis of chiral γ-lactones via a RuPHOX-Ru catalyzed asymmetric hydrogenation of aroylacrylic acids
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DOI: 10.1016/j.tet.2019.05.036
Abstract: Abstract An asymmetric hydrogenation of aroylacrylic acids catalyzed by RuPHOX-Ru catalyst has been developed, affording the corresponding chiral γ-lactones in high yields and with up to 93% ee. The methodology has the advantage of utilizing… read more here.
Keywords: aroylacrylic acids; asymmetric hydrogenation; hydrogenation aroylacrylic; synthesis chiral ... See more keywords