Chalcones Isolated from Arrabidaea brachypoda Flowers as Inhibitors of NorA and MepA Multidrug Efflux Pumps of Staphylococcus aureus
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DOI: 10.3390/antibiotics9060351
Abstract: Bacterial resistance to antibiotics has become a public health issue around the world. The present study aimed to evaluate the antibacterial activity of chalcones isolated from flowers of Arrabidaea brachypoda, and their potential as efflux… read more here.
Keywords: staphylococcus aureus; arrabidaea brachypoda; efflux pumps; nora mepa ... See more keywords
Involvement of Opioid System, TRPM8, and ASIC Receptors in Antinociceptive Effect of Arrabidaea brachypoda (DC) Bureau
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DOI: 10.3390/ijms18112304
Abstract: Arrabidaea brachypoda (DC) Bureau is a medicinal plant found in Brazil. Known as “cipó-una”, it is popularly used as a natural therapeutic agent against pain and inflammation. This study evaluated the chemical composition and antinociceptive… read more here.
Keywords: arrabidaea brachypoda; opioid system; trpm8 asic; asic receptors ... See more keywords
Antileishmanial Activity of Dimeric Flavonoids Isolated from Arrabidaea brachypoda
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DOI: 10.3390/molecules24010001
Abstract: Leishmaniasis are diseases caused by parasites belonging to Leishmania genus. The treatment with pentavalent antimonials present high toxicity. Secondary line drugs, such as amphotericin B and miltefosine also have a narrow therapeutic index. Therefore, there… read more here.
Keywords: arrabidaea brachypoda; antileishmanial activity; dimeric flavonoids; compound ... See more keywords