Silica nanoparticles cause spermatogenesis dysfunction in mice via inducing cell cycle arrest and apoptosis.
Sign Up to like & getrecommendations! Published in 2022 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2022.113210
Abstract: The widespread use of silica nanoparticles (SiNPs) has increased the risk of human exposure, which raised concerns about their adverse effects on human health, especially the reproductive system. Previous studies have shown that SiNPs could… read more here.
Keywords: arrest apoptosis; cell cycle; cell; cycle arrest ... See more keywords
Ovatodiolide isolated from Anisomeles indica induces cell cycle G2/M arrest and apoptosis via a ROS‐dependent ATM/ATR signaling pathways
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2017.09.050
Abstract: ABSTRACT Ovatodiolide was isolated from the traditional Chinese medicinal herb Anisomeles indica, possesses anti‐bacterial and anti‐inflammatory properties; however, the anti‐cancer activity and its mechanisms have been limitedly reported. This study aimed to examine the effect… read more here.
Keywords: dna damage; apoptosis; cell cycle; atm atr ... See more keywords
Paradol Induces Cell Cycle Arrest and Apoptosis in Glioblastoma Cells
Sign Up to like & getrecommendations! Published in 2022 at "Nutrition and Cancer"
DOI: 10.1080/01635581.2022.2028866
Abstract: Abstract Despite being the most common primary malignant tumor of the central nervous system, the prognosis of glioblastoma (GBM) is still remarkably poor. Paradol is a flavor phenolic constituent found in pepper and ginger, with… read more here.
Keywords: apoptosis; arrest; cycle arrest; cell cycle ... See more keywords
Amentoflavone Induces Cell-cycle Arrest, Apoptosis, and Invasion Inhibition in Non-small Cell Lung Cancer Cells
Sign Up to like & getrecommendations! Published in 2021 at "AntiCancer Research"
DOI: 10.21873/anticanres.14893
Abstract: Background/Aim: Amentoflavone, an effective compound derived from medicinal plants, has been shown to boost therapeutic efficacy of chemotherapy in non-small cell lung cancer (NSCLC). However, anti-NSCLC effect of amentoflavone is ambiguous. The major purpose of… read more here.
Keywords: cycle arrest; invasion; inhibition; cell cycle ... See more keywords
Timosaponin AIII Induces G2/M Arrest and Apoptosis in Breast Cancer by Activating the ATM/Chk2 and p38 MAPK Signaling Pathways
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.601468
Abstract: Timosaponin AIII (TAIII), a steroidal saponin, exerts potent anti-tumor activity in various cancers, especially breast cancer. However, the concrete molecular mechanisms of TAIII against breast cancer are still unclear. Here, we find that TAIII triggers… read more here.
Keywords: cancer; arrest apoptosis; atm chk2; breast cancer ... See more keywords
Mechanisms of Cell Cycle Arrest and Apoptosis in Glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10030564
Abstract: Cells of glioblastoma, the most frequent primary malignant brain tumor, are characterized by their rapid growth and infiltration of adjacent healthy brain parenchyma, which reflects their aggressive biological behavior. In order to maintain their excessive… read more here.
Keywords: cycle; cycle arrest; cell cycle; apoptosis glioblastoma ... See more keywords
Anticancer Effects of Fucoxanthin through Cell Cycle Arrest, Apoptosis Induction, Angiogenesis Inhibition, and Autophagy Modulation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232416091
Abstract: Cancer accounts for one in seven deaths worldwide and is the second leading cause of death in the United States, after heart disease. One of the standard cancer treatments is chemotherapy which sometimes can lead… read more here.
Keywords: effects fucoxanthin; cell cycle; anticancer effects; cancer ... See more keywords