Growth arrest specific protein 7 inhibits tau fibrillogenesis.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.03.041
Abstract: Here we show that Gas7 inhibits phosphorylated tau fibrillogenesis by binding to phosphorylated tau at its non-WW domain, presumably F-BAR domain. We revealed that Gas7 binds to the third repeat domain of tau, the core… read more here.
Keywords: arrest specific; fibrillogenesis; growth arrest; specific protein ... See more keywords
The Growth arrest specific 1 (Gas1) gene is transcriptionally regulated by NeuroD1 via two distal E‐boxes
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2018.01.034
Abstract: Abstract Growth arrest specific 1 (GAS1) is a signaling mediator for the development of the central nervous system that works as a co‐receptor for sonic hedgehog (SHH) to induce the amplification of neural progenitors during… read more here.
Keywords: gas1 gene; arrest specific; growth arrest; specific gas1 ... See more keywords
Growth arrest–specific 2 protein family: Structure and function
Sign Up to like & getrecommendations! Published in 2020 at "Cell Proliferation"
DOI: 10.1111/cpr.12934
Abstract: Members of the growth arrest–specific 2 (GAS2) protein family consist of a putative actin‐binding (CH) domain and a microtubule‐binding (GAR) domain and are considered miniversions of spectraplakins. There are four members in the GAS2 family,… read more here.
Keywords: gas2 family; arrest specific; protein family; growth arrest ... See more keywords
Growth Arrest-Specific 6 in Chromophobe Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Oncology"
DOI: 10.1159/000525601
Abstract: Background: Overexpression of tumor-associated growth arrest-specific protein 6 (Gas6) is found in many tumor entities. The prognostic value of Gas6 in renal cell carcinoma (RCC), especially in non-clear cell RCC, is still unclear. Aim: The… read more here.
Keywords: cell carcinoma; cell; renal cell; growth arrest ... See more keywords
Multiple Regulatory Levels of Growth Arrest-Specific 6 in Mucosal Immunity Against an Oral Pathogen
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01374
Abstract: Growth arrest-specific 6 (GAS6) expressed by oral epithelial cells and dendritic cells (DCs) was shown to play a critical role in the maintenance of oral mucosal homeostasis. In this study, we demonstrate that the induction… read more here.
Keywords: gas6; arrest specific; mucosal immunity; growth arrest ... See more keywords
Role of emerging vitamin K‑dependent proteins: Growth arrest‑specific protein 6, Gla‑rich protein and periostin (Review).
Sign Up to like & getrecommendations! Published in 2021 at "International journal of molecular medicine"
DOI: 10.3892/ijmm.2020.4835
Abstract: Vitamin K‑dependent proteins (VKDPs) are a group of proteins that need vitamin K to conduct carboxylation. Thus far, scholars have identified a total of 17 VKDPs in the human body. In this review, we summarize… read more here.
Keywords: protein; arrest specific; periostin; growth arrest ... See more keywords