Growth arrest specific protein 7 inhibits tau fibrillogenesis.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.03.041
Abstract: Here we show that Gas7 inhibits phosphorylated tau fibrillogenesis by binding to phosphorylated tau at its non-WW domain, presumably F-BAR domain. We revealed that Gas7 binds to the third repeat domain of tau, the core… read more here.
Keywords: arrest specific; fibrillogenesis; growth arrest; specific protein ... See more keywords
The Growth arrest specific 1 (Gas1) gene is transcriptionally regulated by NeuroD1 via two distal E‐boxes
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2018.01.034
Abstract: Abstract Growth arrest specific 1 (GAS1) is a signaling mediator for the development of the central nervous system that works as a co‐receptor for sonic hedgehog (SHH) to induce the amplification of neural progenitors during… read more here.
Keywords: gas1 gene; arrest specific; growth arrest; specific gas1 ... See more keywords
Growth arrest–specific 2 protein family: Structure and function
Sign Up to like & getrecommendations! Published in 2020 at "Cell Proliferation"
DOI: 10.1111/cpr.12934
Abstract: Members of the growth arrest–specific 2 (GAS2) protein family consist of a putative actin‐binding (CH) domain and a microtubule‐binding (GAR) domain and are considered miniversions of spectraplakins. There are four members in the GAS2 family,… read more here.
Keywords: gas2 family; arrest specific; protein family; growth arrest ... See more keywords
Growth arrest specific-6 and angiotoxin receptor-like signaling drive oral regenerative wound repair.
Sign Up to like & getrecommendations! Published in 2025 at "Science translational medicine"
DOI: 10.1126/scitranslmed.adk2101
Abstract: Rapid and scarless wound repair is a hallmark of the oral mucosa, yet the cellular and molecular mechanisms that enable this regeneration remain unclear. By comparing populations of murine oral mucosal fibroblasts (OMFs) and facial… read more here.
Keywords: receptor like; regenerative wound; arrest specific; angiotoxin receptor ... See more keywords
Growth Arrest-Specific 6 in Chromophobe Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Oncology"
DOI: 10.1159/000525601
Abstract: Background: Overexpression of tumor-associated growth arrest-specific protein 6 (Gas6) is found in many tumor entities. The prognostic value of Gas6 in renal cell carcinoma (RCC), especially in non-clear cell RCC, is still unclear. Aim: The… read more here.
Keywords: cell carcinoma; cell; renal cell; growth arrest ... See more keywords
Multiple Regulatory Levels of Growth Arrest-Specific 6 in Mucosal Immunity Against an Oral Pathogen
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01374
Abstract: Growth arrest-specific 6 (GAS6) expressed by oral epithelial cells and dendritic cells (DCs) was shown to play a critical role in the maintenance of oral mucosal homeostasis. In this study, we demonstrate that the induction… read more here.
Keywords: gas6; arrest specific; mucosal immunity; growth arrest ... See more keywords
Role of emerging vitamin K‑dependent proteins: Growth arrest‑specific protein 6, Gla‑rich protein and periostin (Review).
Sign Up to like & getrecommendations! Published in 2021 at "International journal of molecular medicine"
DOI: 10.3892/ijmm.2020.4835
Abstract: Vitamin K‑dependent proteins (VKDPs) are a group of proteins that need vitamin K to conduct carboxylation. Thus far, scholars have identified a total of 17 VKDPs in the human body. In this review, we summarize… read more here.
Keywords: protein; arrest specific; periostin; growth arrest ... See more keywords