Elucidating arrhythmogenic right ventricular cardiomyopathy with stem cells
Sign Up to like & getrecommendations! Published in 2022 at "Birth Defects Research"
DOI: 10.1002/bdr2.2010
Abstract: Human stems cells have sparked many novel strategies for treating heart disease and for elucidating their underlying mechanisms. For example, arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disorder that is associated with… read more here.
Keywords: ventricular cardiomyopathy; disease; right ventricular; arrhythmogenic right ... See more keywords
Acylation‐stimulating protein and heart failure progression in arrhythmogenic right ventricular cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.14218
Abstract: Our previous studies suggested that the complement system was critical in the prognosis of arrhythmogenic right ventricular cardiomyopathy (ARVC). The acylation‐stimulating protein (ASP), generated through the alternate complement pathway, was reported to regulate lipogenesis and… read more here.
Keywords: heart failure; ventricular cardiomyopathy; stimulating protein; acylation stimulating ... See more keywords
Analysis of local ventricular repolarization using unipolar recordings in patients with arrhythmogenic right ventricular cardiomyopathy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Interventional Cardiac Electrophysiology"
DOI: 10.1007/s10840-019-00594-z
Abstract: Purpose In arrhythmogenic right ventricular cardiomyopathy (ARVC), abnormal electroanatomic mapping (EAM) areas are proportional to extent of T-wave inversion on 12-lead ECG. We aimed to evaluate local repolarization changes and their relationship to EAM substrate… read more here.
Keywords: arvc; ventricular cardiomyopathy; using unipolar; right ventricular ... See more keywords
Pathogenic variants in plakophilin-2 gene (PKP2) are associated with better survival in arrhythmogenic right ventricular cardiomyopathy.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of applied genetics"
DOI: 10.1007/s13353-021-00647-y
Abstract: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is mainly caused by mutations in genes encoding desmosomal proteins. Variants in plakophilin-2 gene (PKP2) are the most common cause of the disease, associated with conventional ARVC phenotype. The study… read more here.
Keywords: arvc; ventricular cardiomyopathy; right ventricular; pkp2 ... See more keywords
Sub–mitral valve aneurysm ventricular tachycardia masquerading as arrhythmogenic right ventricular cardiomyopathy
Sign Up to like & getrecommendations! Published in 2021 at "HeartRhythm Case Reports"
DOI: 10.1016/j.hrcr.2021.05.014
Abstract: Clinical re-review of all suspected ARVC cases should always be performed, especially when more Introduction The underlying etiology of ventricular tachycardia (VT) is essential for developing proper risk stratification and treatment strategies. Assessment of an… read more here.
Keywords: ventricular tachycardia; etiology; ventricular cardiomyopathy; right ventricular ... See more keywords
Ablation compared with drug therapy for recurrent ventricular tachycardia in arrhythmogenic right ventricular cardiomyopathy: Results from a multicenter study.
Sign Up to like & getrecommendations! Published in 2019 at "Heart rhythm"
DOI: 10.1016/j.hrthm.2018.10.016
Abstract: BACKGROUND The comparative efficacy of antiarrhythmic drug (AAD) therapy vs ventricular tachycardia (VT) ablation in arrhythmogenic right ventricular cardiomyopathy (ARVC) is unknown. OBJECTIVE We compared outcomes of AAD and/or β-blocker (BB) therapy with those of… read more here.
Keywords: ventricular tachycardia; ablation; drug; underwent ablation ... See more keywords
Clinical characteristics and determinants of phenotype in TMEM43 Arrhythmogenic right ventricular cardiomyopathy type 5.
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DOI: 10.1016/j.hrthm.2020.01.035
Abstract: BACKGROUND Arrhythmogenic right ventricular cardiomyopathy type V (ARVC-5) is the most aggressive heterozygous form of ARVC. It is predominantly caused by a fully penetrant mutation (p.S358L) in the non-desmosomal gene TMEM43 - endemic to Newfoundland,… read more here.
Keywords: ventricular cardiomyopathy; phenotype tmem43; right ventricular; background ... See more keywords
Exercise and Arrhythmic Risk in TMEM43 p.S358L Arrhythmogenic Right Ventricular Cardiomyopathy.
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DOI: 10.1016/j.hrthm.2020.02.028
Abstract: BACKGROUND High level exercise has been associated with a malignant phenotype in desmosomal and genotype negative forms of arrhythmogenic right ventricular cardiomyopathy (ARVC). This is the first study to examine this issue with ARVC secondary… read more here.
Keywords: tmem43 s358l; exercise; risk; arrhythmogenic right ... See more keywords
Effect of Preload Reducing Therapy on Right Ventricular Size and Function in Patients with Arrhythmogenic Right Ventricular Cardiomyopathy.
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DOI: 10.1016/j.hrthm.2021.03.018
Abstract: BACKGROUND Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is an important cause of sudden cardiac death in young people and athletes. Thus far, no treatment has proven to slow the progression of the disease. Preload reducing agents… read more here.
Keywords: ventricular cardiomyopathy; reducing agents; right ventricular; preload ... See more keywords
Clinical Outcomes of Catheter Ablation of Ventricular Tachycardia in Patients with Arrhythmogenic Right Ventricular Cardiomyopathy: Insights from the Johns Hopkins ARVC Program.
Sign Up to like & getrecommendations! Published in 2021 at "Heart rhythm"
DOI: 10.1016/j.hrthm.2021.04.028
Abstract: BACKGROUND Prior studies of radiofrequency catheter ablation (RFA) of ventricular tachycardia (VT) in arrhythmogenic right ventricular cardiomyopathy (ARVC) patients, relying on limited numbers of procedures, have not reported VT-free survival in parallel for single and… read more here.
Keywords: ventricular tachycardia; ablation; right ventricular; rfa ... See more keywords
Systematic review: Impact of the new task force criteria in the diagnosis of arrhythmogenic right ventricular cardiomyopathy.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2017.03.069
Abstract: BACKGROUND Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited disorder of cardiac desmosomes associated with ventricular arrhythmias and sudden cardiac death. The clinical diagnosis is problematic and relies on a complex criteria composed of clinical… read more here.
Keywords: ventricular cardiomyopathy; right ventricular; force criteria; three studies ... See more keywords