Combined effect of polymorphisms of MTHFR and MTR and arsenic methylation capacity on developmental delay in preschool children in Taiwan
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Toxicology"
DOI: 10.1007/s00204-020-02745-y
Abstract: Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MTR) are related to cognitive dysfunction and mental disability. These genes, along with folate and vitamin B12 levels, are regulators of one-carbon metabolism, which synthesizes S-adenosylmethionine (SAM)… read more here.
Keywords: developmental delay; arsenic methylation; methylation capacity; delay ... See more keywords
Arsenite methyltransferase (AS3MT) polymorphisms and arsenic methylation in children in rural Bangladesh
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.08.020
Abstract: Background: Arsenic methylation efficiency, a susceptibility factor for arsenic toxicity, is in adults partly explained by variation in arsenite methyltransferase (AS3MT) gene. Little is known about the role of AS3MT for children's arsenic methylation. Objectives:… read more here.
Keywords: methylation children; arsenic methylation; methylation; as3mt polymorphisms ... See more keywords
Methanogens-Driven Arsenic Methylation Preceding Formation of Methylated Thioarsenates in Sulfide-Rich Hot Springs.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c08814
Abstract: Hot springs represent a major source of arsenic release into the environment. Speciation is typically reported to be dominated by arsenite, arsenate, and inorganic thiolated arsenates. Much less is known about the relevance and formation… read more here.
Keywords: methylated thioarsenates; arsenic methylation; sulfide rich; formation methylated ... See more keywords
Proanthocyanidins Antagonize Arsenic-Induced Oxidative Damage and Promote Arsenic Methylation through Activation of the Nrf2 Signaling Pathway
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DOI: 10.1155/2019/8549035
Abstract: Purpose To investigate the effects of grape seed proanthocyanidin extract (GSPE) on oxidative damage and arsenic (As) methylation and to clarify the role of Nrf2 in the process. Methods L-02 cells were treated with arsenic… read more here.
Keywords: arsenic methylation; methylation; oxidative damage; group ... See more keywords
Relative miRNA and mRNA expression involved in arsenic methylation
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DOI: 10.1371/journal.pone.0209014
Abstract: Three arsenic species in urine are measured using an atomic absorption spectrophotometer. RT-PCR is performed to detect the expression levels of AS3MT, 3 miRNAs, and 17 relative mRNAs in 43 workers producing arsenic trioxide, 36… read more here.
Keywords: arsenic methylation; relative mirna; mir 548c; expression ... See more keywords