Metabolomic assessment of arsenite toxicity and novel biomarker discovery in early development of zebrafish embryos.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2018.03.014
Abstract: CONTEXT Arsenic poisoning commonly occurs through exposure to water contaminated with arsenic and causes long-term symptoms. Of all the arsenic derivatives, arsenite is the one of the most toxic compounds. However, the toxicity of arsenite… read more here.
Keywords: embryonic zebrafish; toxicity novel; metabolomic assessment; zebrafish ... See more keywords
Arsenite toxicity is regulated by queuine availability and oxidation-induced reprogramming of the human tRNA epitranscriptome
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2123529119
Abstract: Significance Arsenic is a centuries-old, naturally occurring toxicant, and its cellular effect is still poorly understood. The significance of this work is three-fold. First, among a battery of oxidizing and alkylating agents, arsenite exposure caused… read more here.
Keywords: toxicity regulated; arsenite toxicity; trna epitranscriptome; epitranscriptome ... See more keywords