Arsenoplatin-1 Is a Dual Pharmacophore Anticancer Agent.
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DOI: 10.1021/jacs.8b13681
Abstract: Arsenoplatins are adducts of two chemically important anticancer drugs, cisplatin and arsenic trioxide, that have a Pt(II) bond to an As(III) hydroxide center. Screens of the NCI-60 human tumor cell lines reveal that arsenoplatin-1 (AP-1),… read more here.
Keywords: anticancer agent; bond; dual pharmacophore; arsenoplatin dual ... See more keywords