Change of right ventricular systolic pressure can indicate dasatinib‐induced pulmonary arterial hypertension in chronic myeloid leukemia
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.3588
Abstract: We investigated the feasibility of the clinical application of non‐invasive transthoracic echocardiography for diagnosis of pulmonary arterial hypertension induced by dasatinib (D‐PAH) in chronic myeloid leukemia (CML). read more here.
Keywords: pulmonary arterial; myeloid leukemia; arterial hypertension; chronic myeloid ... See more keywords
An emerging class of new therapeutics targeting TGF, Activin, and BMP ligands in pulmonary arterial hypertension
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DOI: 10.1002/dvdy.478
Abstract: Pulmonary arterial hypertension (PAH) is an often fatal condition, the primary pathology of which involves loss of pulmonary vascular perfusion due to progressive aberrant vessel remodeling. The reduced capacity of the pulmonary circulation places increasing… read more here.
Keywords: bmp signaling; arterial hypertension; bmp; pulmonary arterial ... See more keywords
Renal replacement therapy as a therapeutic option for right heart failure in severe pulmonary arterial hypertension.
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DOI: 10.1002/ehf2.13945
Abstract: Pulmonary arterial hypertension (PAH) is a progressively life-threatening disease that causes right heart failure (RHF). Renal dysfunction frequently complicates PAH with RHF and is associated with a worse prognosis. Renal replacement therapy (RRT) may be… read more here.
Keywords: pah; arterial hypertension; pulmonary arterial; heart failure ... See more keywords
Circulating plasmablasts are elevated and produce pathogenic anti‐endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Immunology"
DOI: 10.1002/eji.201747460
Abstract: Idiopathic pulmonary arterial hypertension (IPAH) is a devastating pulmonary vascular disease in which autoimmune and inflammatory phenomena are implicated. B cells and autoantibodies have been associated with IPAH and identified as potential therapeutic targets. However,… read more here.
Keywords: idiopathic pulmonary; arterial hypertension; endothelial cell; pulmonary arterial ... See more keywords
Decrease in LINC00963 attenuates the progression of pulmonary arterial hypertension via microRNA‐328‐3p/profilin 1 axis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24383
Abstract: Pulmonary arterial hypertension (PAH) is a severe cardiopulmonary disease characterized by vascular hyperplasia and remodeling. Long noncoding RNA LINC00963 can regulate cell proliferation and metastasis in nonsmall cell lung cancer. However, the function of LINC00963… read more here.
Keywords: arterial hypertension; progression; pulmonary arterial; decrease linc00963 ... See more keywords
A high prevalence of arterial hypertension in patients with mitochondrial diseases
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DOI: 10.1002/jimd.12195
Abstract: The prevalence of arterial hypertension in mitochondrial diseases remains unknown. Between January 2000 and May 2014, we retrospectively included patients with genetically proven mitochondrial diseases. We recorded clinical, genetic and cardiac exploration data, including the… read more here.
Keywords: arterial hypertension; mitochondrial diseases; prevalence; prevalence arterial ... See more keywords
A unique gut microbiota signature in pulmonary arterial hypertension: A pilot study
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12051
Abstract: Abstract Pulmonary arterial hypertension (PAH) is a progressive, ultimately fatal cardiopulmonary disease associated with a number of physiologic changes, which is believed to result in imbalances in the intestinal microbiota. To date, comprehensive investigational analysis… read more here.
Keywords: arterial hypertension; microbiota; pulmonary arterial; pah ... See more keywords
Long‐term safety of a structured transition protocol from parenteral prostanoids to selexipag in pulmonary arterial hypertension
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12058
Abstract: Abstract There was no structured method for safely transition from parenteral prostanoids to oral medication. We enrolled 37 idiopathic/hereditary pulmonary arterial hypertension patients receiving triple combination therapy including parenteral prostanoids into structured transition program to… read more here.
Keywords: long term; arterial hypertension; term safety; pulmonary arterial ... See more keywords
The exercise in pulmonary arterial hypertension (ExPAH) study: A randomized controlled pilot of exercise training and multidisciplinary rehabilitation in pulmonary arterial hypertension
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DOI: 10.1002/pul2.12069
Abstract: Abstract Pulmonary hypertension (PH) is characterized by progressive dyspnea, fatigue, and reduced exercise capacity. Despite medical treatment, outcomes remain poor. While exercise training is well established in patients with heart failure, it is less established… read more here.
Keywords: arterial hypertension; hypertension; pilot; pulmonary arterial ... See more keywords
Maternal and fetal outcomes of pregnant women with pulmonary arterial hypertension associated with congenital heart disease in Beijing, China: A retrospective study
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DOI: 10.1002/pul2.12079
Abstract: Abstract As pulmonary arterial hypertension associated with congenital heart disease (PAH‐CHD) may increase maternal and fetal risk, this study explored the pregnancy outcomes of Chinese women with PAH‐CHD. The clinical data of pregnant women with… read more here.
Keywords: arterial hypertension; maternal fetal; pregnant women; pulmonary arterial ... See more keywords
Prospective clinical assessment of patients with pulmonary arterial hypertension switched from bosentan to macitentan (POTENT)
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DOI: 10.1002/pul2.12083
Abstract: Abstract Even though pulmonary arterial hypertension (PAH) remains an incurable disease, the combination of PAH‐specific therapies allowed evolving from symptom‐based strategies to others aiming to move patients to low‐risk conditions. Endothelin‐1 (ET‐1) receptor antagonists emerged… read more here.
Keywords: arterial hypertension; macitentan; potent; pulmonary arterial ... See more keywords